We're back for another week of pairing teammates together and hoping they have the required chemistry to pay off in our NFL DFS lineups. While there are ways to win on DraftKings and FanDuel without stacks, it's often a lot more fun when the stacks pay off big time. A week ago, our Jake Luton and DJ Chark stack likely wasn't used by many, but if you took the risk, you had a good chance of cashing. In Week 10, even our GPP stacks aren't that bold, but we have several options for you as always.
This week, our cash-game stacks all feature one quarterback with one receiver, while we've allowed the more creative stacks to reside in the tournament section. That means if you're looking to stack a trio of players or maybe a running back with a defense, it might be best to do that in tournaments this week (although we make the case for one of those GPP stacks to work in cash games, too).
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Week 10 NFL DFS Picks: Top cash game stacks for DraftKings, FanDuel
QB Aaron Rodgers and WR Davante Adams, Packers vs. Jaguars (FD/DK stack)
This is about as automatic a stack as you'll find this week. It will be highly played in pretty much every format on every site, and that's in part because Lamar Jackson and Patrick Mahomes both aren't on this slate. That's fine, though — it's worth having some shares of this pairing in your lineups.
Adams doesn't really even need justification at this point as he goes out time and again and approaches double-digit catches and looks pretty much unguardable. Rodgers is an easy play, too.
Jacksonville has allowed the third-most DK and FD points per game to QBs, and Adams should get most of that Rodgers production heading his way in Week 10.
QB Josh Allen and WR Stefon Diggs, Bills @ Cardinals (DK stack)
A week after Allen threw for 415 yards and scored four total touchdowns, he'll be a popular DFS play, too. We wouldn't invest as heavily in this combo as we would in the Packers, but Allen's rushing ability will always make him worth playing against a middling (at best) defense.
This game should also turn into a shootout, just like the Bills' 44-34 win over Seattle in Week 9. That will bode well for Allen's favorite target, Diggs, who combines a great floor with a solid ceiling to make him worthwhile at his price.
QB Drew Lock and WR Jerry Jeudy OR WR Tim Patrick, Broncos @ Raiders (FD stack)
Lock is one of those guys that doesn't provide a calm viewing experience but normally ends the day with solid fantasy numbers. In a lot of ways, he feels more like a tournament play, but he can work in cash games if you're looking to pay up at RB and WR.
The Raiders have been a bottom-10 defense this season in terms of allowing fantasy points to quarterbacks, and Lock has broken 20 FD points in back-to-back weeks. He'll likely make it three in a row, and the tricky part will be choosing the correct receiver to pair with him.
In a tournament, you could go all-in and use Jeudy and Patrick. In a cash game, it's pretty much a toss-up, so maybe see which salary fits better after you construct most of the rest of your lineup.
Week 10 DraftKings, FanDuel Picks: Best stacks for daily fantasy football GPPs/tournaments
QB Jared Goff, WR Robert Woods and WR Cooper Kupp, Rams vs. Seahawks (FD/DK stack)
Goff is surprisingly affordable, making him a worthy cash-game QB against the defense allowing the most FD points to quarterbacks this season.
Just note that this is one of the safest tournament stacks you'll find this week. Seattle allows almost 50 FD points per game to wide receivers, meaning there's plenty to go around for both Woods and Kupp on the receiving end from Goff, who isn't a stranger to games where throwing the ball 50 times is the best strategy. Some quiet weeks from Goff lately will hopefully keep his ownership from being too high, but even if these three players are all highly owned, it's likely worth it.
QB Carson Wentz, WR Travis Fulgham and WR Jalen Reagor, Eagles @ Giants (FD stack)
This stack will not be heavily used at all despite a friendly matchup. That's because almost no one will throw both Fulgham and Reagor in a lineup with Wentz -- and that's why you should. These two wideouts are still learning how to co-exist, but they have different enough skillsets that it can work. Fulgham provides the big, athletic target, while Reagor can run away from anyone on the field.
When these teams faced off on Oct. 22, Wentz scored 28.76 FD points, and that was with injuries holding back Philly's offense. With a little more health now, expect good things out of the Eagles in Week 10.
RB Alvin Kamara and DEF New Orleans Saints vs. 49ers (DK stack)
Kamara is usually a safe play, and the Saints defense has a good matchup here against Nick Mullens. Kamara's high price and relatively tough matchup might keep his ownership down, and because people don't often think of RB/Defense stacks, this can work in a tournament.
The biggest key here will be finding Kamara the requisite touches to dominate. His Week 9 numbers are a bit hard to interpret because, while it was Michael Thomas' first game back, it was also a total blowout. Hopefully things are more normal in Week 10, leading to about 20 touches for Kamara to make big things happen on.